Description
Specifications
| Clone | IHC623 |
| Source | Mouse Monoclonal |
| Positive Control | Breast, Colon, Associated Adenocarcinomas |
| Dilution Range | 1:200 |
Mucin 1 (MUC1) is a membrane-bound glycoprotein involved in a number of protective and cell-signaling functions, including cell-cell adhesion, proliferation, motility, invasion, and survival. Overexpression of MUC1 is clinically indicated in breast carcinomas, papillary thyroid carcinomas, and thymic carcinomas, and reports have named MUC1 as a useful marker for differentiating thymic carcinoma from type B3 thymoma. The expression of MUC1 is correlated with the grade of malignancy in thymic epithelial tumors, and loss of MUC1 expression has been associated with reactive gastropathy. MUC1 is not expressed in normal human epidermis, but has been detected in the epidermis of psoriatic plaques of biopsies from patients diagnosed with psoriasis vulgaris.
| Clone | IHC623 |
| Source | Mouse Monoclonal |
| Positive Control | Breast, Colon, Associated Adenocarcinomas |
| Dilution Range | 1:200 |
DBCO-NHCO-PEG13-NHS ester is a long chain PEG linker containing NHS ester that is able to react specifically and efficiently with primary amines to form astable amide bond. The hydrophilic PEG13 arm improves water solubility and can also provide a long and flexible connection that minimizes steric hindrance during ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
DBCO-NHCO-PEG13-NHS ester is a long chain PEG linker containing NHS ester that is able to react specifically and efficiently with primary amines to form astable amide bond. The hydrophilic PEG13 arm improves water solubility and can also provide a long and flexible connection that minimizes steric hindrance during ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
PACE OneStep RT-PCR Master Mix combines reverse transcription (RT) and PCR in a single reaction. This advanced master mix simplifies workflows by eliminating the need for separate reactions for reverse transcription of RNA to cDNA, and PCR amplification from the newly generated cDNA. PACE OneStep RT-PCR Master Mix is highly efficient and sensitive, enabling detection of low-abundance RNA targets, particularly useful for applications such as gene expression analysis and viral RNA detection. PACE OneStep RT-PCR Master Mix demonstrates robust performance across a wide range of RNA templates and can be employed for both routine and challenging samples.
Name of Product
HAMA – Human Anti Mouse
Antibodies Detection Kit
Catalog Number
MQHM Z
Short Info
Lateral Flow Assay designed for the detection of Human Anti Mouse Antibodies (HAMA) in human serum.
This product is only available in the EU!
Method/Platform
Lateral Flow
Range/Assay Sensivity
97%
Test Principle
The HAMA Detection Kit is an immunoassay designed for qualitative determination of Human Anti Mouse Antibodies in human serum.
HAMA from patient’s sample bind first to mouse antibodies which are conjugated to gold nanoparticles.
In a second step the HAMA will be caught by mouse IgG antibodies, coated on the Test Line (T) of the nitrocellulose membrane.
In the presence of the HAMA-conjugat-complex a band becomes visible at the location of the Test Line (T).
The surplus of gold particles continues to migrate through the membrane and is captured at the Control Line (C) by specific antibodies.
Color’s intensitiy of the test line is directly proportional to the HAMA concentration in the sample.
Brief Instructions
Storage
2-8°C
Components
HAMA Test Unit, Chase Buffer, Evaluation Cards
5 tests
Lateral Flow Assay designed for the detection of Human Anti Mouse Antibodies (HAMA) in human serum.