Opentrons Thermocycler GEN2 Seals are adhesive-backed Ethylene Propylene Diene Monomer (EPDM) seals designed for use with the fully-automated Thermocycler Module GEN2. They come in a package of 10 seals. These seals need to be applied to the hood of the Thermocycler and can be reused up to 20 times. Opentrons Thermocycler GEN2 Seals need to be sterilized before each use.
Note, if you have a Thermocycler Module GEN1, please use the Thermocycler GEN1 Seals.
Opentrons Thermocycler GEN2 Seals are adhesive-backed Ethylene Propylene Diene Monomer (EPDM) seals designed for use with the fully-automated Thermocycler Module GEN2. They come in a package of 10 seals. These seals need to be applied to the hood of the Thermocycler and can be reused up to 20 times. Opentrons Thermocycler GEN2 Seals need to be sterilized before each use.
Note, if you have a Thermocycler Module GEN1, please use the Thermocycler GEN1 Seals.
AchE Inhibitor Screening Kit (Colorimetric) provides a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of AchE inhibitors.
ACETYLCHOLINESTERASE (EC 3.1.1.7, AChE), also known as RBC cholinesterase, is found primarily in the blood and neural synapses. AChE catalyzes the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid, a reaction necessary to allow a cholinergic neuron to return to its resting state after activation. Inhibition of the enzyme leads to acetylcholine accumulation, hyperstimulation of nicotinic and muscarinic receptors, and disrupted neurotransmission. AChE inhibition is an important target for the management of Alzheimer’s disease. In addition to Alzheimer’s disease, AChE inhibitors have been useful in the diagnosis or treatment of diseases such as glaucoma, myasthenia gravis, bladder distention, and more.
The Attogene Acetylcholinesterase Inhibitor Assay is based on an improved Ellman method, in which thiocholine produced by the action of acetylcholinesterase forms a yellow color with 5,5′-dithiobis(2-nitrobenzoic acid). The intensity of the product color, measured at 412nm, is proportionate to the enzyme activity in the sample.
The Acetylcholinesterase Assay Kit provides a convenient method for the detecting AChE activity and screening for inhibitors.
The kit uses DTNB to quantify the thiolcholine produced from the hydrolysis of acetylthiolcholine by AChE.
Propargyl-PEG2-alcohol has propargyl and alcohol end groups. The propargyl can participate in copper-catalyzed Click Chemistry reactions with azides. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Propargyl-PEG2-alcohol has propargyl and alcohol end groups. The propargyl can participate in copper-catalyzed Click Chemistry reactions with azides. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.