DBCO-STP Ester is an amine-reactive, water-soluble labeling reagent, including a DBCO group for click reactions with azide groups on target molecules and an STP ester group, which can react with primary amines, forming covalent amide bonds. STP esters typically display much better stability toward hydrolysis in aqueous media, resulting in more efficiency and better reproducible labeling of biopolymers. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
DBCO-STP Ester is an amine-reactive, water-soluble labeling reagent, including a DBCO group for click reactions with azide groups on target molecules and an STP ester group, which can react with primary amines, forming covalent amide bonds. STP esters typically display much better stability toward hydrolysis in aqueous media, resulting in more efficiency and better reproducible labeling of biopolymers. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
| Clone | IHC610 |
| Source | Mouse Monoclonal |
| Positive Control | Tonsil |
| Dilution Range | 1:200 |
GeneAb™ Kappa
| Clone | IHC538 |
| Source | Mouse Monoclonal |
| Positive Control | Tonsil, Lymph Node |
| Dilution Range | 1:200 |
Cluster of differentiation 5 (CD5) is expressed in high levels on the surface of T cells, while controversy surrounds the expression levels and role of CD5 in B cells. As a part of a diagnostic panel, its utility lies predominantly as a marker for T cells, with over 70% of T cell neoplasms expressing CD5. In particular, it is correlated with chronic lymphocytic leukemia/small lymphocytic lymphomas, mantle cell lymphoma, as well as a subset of diffuse large B cell lymphomas. CD5 demonstrates positive expression in thymic carcinomas, and is not as sensitive as CD3. CD5 also has value as a prognostic indicator, being associated with poor prognosis in acute T cell lymphoblastic leukemia.
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