Description
Specifications
| Clone | IHC044 |
| Source | Mouse Monoclonal |
| Positive Control | Benign Urothelium |
| Dilution Range | 1:200 |
Cluster of differentiation 44 (CD44) is a glycoprotein receptor for hyaluronic acid, which plays a fundamental role in cellular adhesion, stromal binding, migration, and cell-cell interactions. Studies have suggested that the CD44-hyaluronate interaction is central to tumor invasiveness. Positive staining with Anti-CD44 is implicated in a multitude of different cancer types, including breast, prostatic, renal cell, colonic, hepatocellular, and genitourinary carcinomas, as well as Non-Hodgkin’s Lymphoma, metastatic melanoma, gastric cancer, and some soft tissue tumors. It has also been demonstrated that there is a positive correlation between tumor progression and increased expression of CD44v, a high molecular weight CD44 isoform that has been described in epithelial cells. Given the expression of CD44 in a wide range of cancers, the most practical application of CD44 immunostaining is its use in discriminating between urothelial transitional cell carcinoma in situ from non-neoplastic changes in the urothelium.
| Clone | IHC044 |
| Source | Mouse Monoclonal |
| Positive Control | Benign Urothelium |
| Dilution Range | 1:200 |
TCO-PEG8-DBCO is a heterobifunctional click chemistry reagent containing a TCO and a DBCO moiety. TCO group specifically and efficiently reacts with terrahydrazine at fast speed. DBCO is very reactive toward Azide through copper free click chemistry, the PEG spacer increases the aqueous solubility of the reagent. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
TCO-PEG8-DBCO is a heterobifunctional click chemistry reagent containing a TCO and a DBCO moiety. TCO group specifically and efficiently reacts with terrahydrazine at fast speed. DBCO is very reactive toward Azide through copper free click chemistry, the PEG spacer increases the aqueous solubility of the reagent. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
We accelerate RT-PCR for SARS-CoV-2 detection and make Covid-19 research easier!
The Volcano product family supports this goal with optimized reaction components for sensitive and reliable results. The key driver is an engineered, truly thermostable Taq DNA polymerases with reverse transcriptase activity. Have a look at the products or contact us directly for support optimizing your products:
The Volcano product family supports this goal with optimized reaction components for sensitive and reliable results. The key driver is an engineered, truly thermostable Taq DNA polymerases with reverse transcriptase activity. Have a look at the products or contact us directly for support optimizing your products:
