
Description
Specifications
Clone | IHC044 |
Source | Mouse Monoclonal |
Positive Control | Benign Urothelium |
Dilution Range | 1:200 |
Cluster of differentiation 44 (CD44) is a glycoprotein receptor for hyaluronic acid, which plays a fundamental role in cellular adhesion, stromal binding, migration, and cell-cell interactions. Studies have suggested that the CD44-hyaluronate interaction is central to tumor invasiveness. Positive staining with Anti-CD44 is implicated in a multitude of different cancer types, including breast, prostatic, renal cell, colonic, hepatocellular, and genitourinary carcinomas, as well as Non-Hodgkin’s Lymphoma, metastatic melanoma, gastric cancer, and some soft tissue tumors. It has also been demonstrated that there is a positive correlation between tumor progression and increased expression of CD44v, a high molecular weight CD44 isoform that has been described in epithelial cells. Given the expression of CD44 in a wide range of cancers, the most practical application of CD44 immunostaining is its use in discriminating between urothelial transitional cell carcinoma in situ from non-neoplastic changes in the urothelium.
Clone | IHC044 |
Source | Mouse Monoclonal |
Positive Control | Benign Urothelium |
Dilution Range | 1:200 |
Discover our Tryptose Phosphate Broth, formulated to support the cultivation of fastidious microorganisms, including Haemophilus influenzae and Neisseria species. Ideal for microbiological research, pharmaceutical testing, and vaccine production.
Discover our Tryptose Phosphate Broth, formulated to support the cultivation of fastidious microorganisms, including Haemophilus influenzae and Neisseria species. Ideal for microbiological research……
Norgen’s Legionella sp. TaqMan PCR Lyophilized Kit is designed for the detection of Legionella sp. specific DNA in a real-time PCR based on the use of TaqMan® technology. The lyophilized format is designed to ship the kit at ambient temperature.
Norgen’s Legionella sp. TaqMan Lyophilized Probe/Primer and Control Set is designed for the detection of Legionella sp. specific DNA in a real-time PCR based on the use of TaqMan® technology. The lyophilized format is designed to ship the kit at ambient temperature.
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Component | Cat. TM64450L (100 preps) | Cat. TM64410L (100 preps) |
---|---|---|
MDx TaqMan 2X PCR Master Mix (Lyo) | 4 x 350 μL | – |
Legionella sp. Primer & Probe Mix (Lyo) | 280 μL | 280 μL |
Legionella sp. Positive Control (Lyo) | 150 μL | 150 μL |
Nuclease-Free Water (Negative Control) | 3 x 1.25 mL | 1 x 1.25 mL |
Product Insert | 1 | 1 |
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