Sulfo DBCO-PEG4-Amine is a water-soluble carboxyl-reactive building block with extended PEG spacer arm. In the presence of of activators (e.g. EDC, or HATU), this reagent can be used to derivatize carboxyl groups or activated esters (e.g. The NHS ester) through a stable amide bond. The hydrophilic sulfonated spacer arm greatly improves water solubility of DBCO derivatized molecules and a provides a long and flexible connection. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Detail
Sulfo DBCO-PEG4-Amine is a water-soluble carboxyl-reactive building block with extended PEG spacer arm. In the presence of of activators (e.g. EDC, or HATU), this reagent can be used to derivatize carboxyl groups or activated esters (e.g. The NHS ester) through a stable amide bond. The hydrophilic sulfonated spacer arm greatly improves water solubility of DBCO derivatized molecules and a provides a long and flexible connection. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Brucella abortus is an intracellular, blood-borne parasite. It is a Gram-negative coccobacillus that causes an infectious and contagious disease called Brucellosis. The disease primarily affects cattle but it can also be transmitted to humans from infected animals and consuming their products. The disease can lead to great economic loss especially in the dairy and agricultural industry. The Brucella abortus genome contains two DNA chromosomes in a circular confirmation; the first chromosome is approximately 2.1 Mb and the second chromosome is approximately 1.2Mb. Unusually it does not contain any plasmids or genomic islands that relate to pathogenicity and lacks many other genes that code for common virulence factors including capsules, fimbriae, exotoxins, cytolysins, resistance forms, or antigenic variation. The most common mode of transmission to humans is through the ingestion of unpasteurized milk and cheese products as the bacteria are present in the milk glands of infected female cows. In cattle transmission can also be through ingestion but in addition, the bacteria can persist in the reproductive tracts of males, namely seminal vesicles, ampullae, testicles, and epididymides, allowing sexual transmission. In humans the bacteria enter macrophages by phagocytosis and then live in compartments of vacuolar space along the endoplasmic reticulum. They persist by inhibiting host apoptosis and go onto form chronic disease causing lesions in the liver, spleen, bone marrow and kidneys. In cattle the bacteria additionally infect the trophoblast epithelial cells, which provide nutrition to the embryo. The trophoblast cells eventually lyse, releasing further bacteria into the blood stream of the embryo. The B. abortus cells in the blood stream go on to colonize the placenta and fetus in pregnant female cows, resulting in abortion of the fetus. Abortion can also result from insufficient anti-Brucella activity in the amniotic fluid. In humans, the disease can be either acute or chronic and some of the symptoms include fluctuating fever, chills, sweating, headache, muscle pain and weight loss. Once a person becomes infected they are prescribed a combination of tetracycline and streptomycin for 3-6 weeks. In cattle, additional symptoms include arthritic joints and retained after-birth.
Document
Exceptional value for money
Rapid detection of all clinically relevant subtypes
Positive copy number standard curve for quantification
Highly specific detection profile
High priming efficiency
Broad dynamic detection range (>6 logs)
Sensitive to < 100 copies of target
Accurate controls to confirm findings
Yingtai pilot-type freeze dryer completely simulates the technical requirements of the industrial freeze dryer,with a compact and reasonable design,a large redundancy range,and conforms to GMP and FDA standards.The ice condensation capacity is 4~18kg,and the WRL controller and liquid temperature control shelf are adopted,so that the process of pre-freezing and freeze-drying can be precisely controlled on the main machine,and the process results are quite comparable with the production machine.In addition to supporting the eutectic point test system,pressure rise and pressure comparison method to determine the freeze-drying end point and freeze-drying curve recording software,hallan pilot-type freeze dryer can also be equipped with engineering WRL control software to directly Graphical computer control the freeze-drying process.It can be configured with H202 sterilization and high-pressure steam sterilization orintegrated glove box system, which can be used for clean room operation through the wall.The cold trap and freeze-drying chamber are all designed with 316L stainless steel to ensure the cleanliness of the chamber and good ultimate vacuum and vacuum leakage rate to the greatest extent.
Refrigeration Series
● Dual compressors,Secop special compressors,air cooling (water cooling system is optional)
Silicone oil conducts heat,with uniform temperature and accuracy up to 0.1°C.Silicone oil has a wide temperature range,up to-100°C~+600°C.
● Shelf refrigeration system and cold trap refrigeration system are completely independent,without any switching,refrigeration temperature is lower and more stable.
Vacuum series
● Vacuum pump:German Pfeiffer anti-corrosion,anti-oil return function vacuum pump.(Vacuum pump can be selected according to user needs)
● Pumping rate:9m³/h~62m³/h,multiple specifications are optional,the ultimate vacuum can reach 2×10-3mbar,and the oil mist filter is standard.
● The vacuum pipelines are all high-vacuum stainless steel vacuum tubes, which can effectively prevent vacuum leakage and corrosion.
● The double anti-oil return device completely eliminates the damage and
equipment and samples.
● Automatic backfill air device,the system has a built-in High efficiency particulate air(HEPA)filter to ensure the complete cleanliness of backfill air.
● The vacuum stabilization system can stabilize the vacuum degree of the freeze-drying process through the micro-pass vacuum control valve to ensure that the samples will not be affected by excessive fluctuations in the vacuum degree.
● Condensed liquid collection and discharge system,automatically completes the collection and discharge of condensed liquid after freeze-drying.
Control SystemCharacteristic
● Control:Automatic/Manual
● Can store at least 100 independent freeze-drying programs,each program contains 32 program segments (Can be
customized according to user needs),each program segment corresponds to a processing stage (pre-freezing,main
drying,post-drying).and Include the following segment values:Cycles,shelf temperature,vacuum and safety pressure
● All the equipment can be recorded in real time and the corresponding freeze-drying curves and data tables can be generated after the end.The records of all data and curves comply with the corresponding regulations and standards.
● It has hierarchical management authority,hierarchical management allocation authority and usage process tracking authority
● Remote System
O Fully support 2G/4G/GSM/Wi-Fivarious connection modes
o Users can remotely view all data on the device and operate it
o Technicians can remotely perform maintenance and fault detection on equipment,and can remotely guide and train users
o Can remotely upgrade and change the system of the equipment
(Optional)Sufficient amount and time for the program to run itself
User function customization
Can be customized and modified according to user needs
Sterilization method
HzOz/steam sterilization
Note:”/”optional.Pilot models can be customized according to user needs
Document
Yingtai pilot-type freeze dryer completely simulates the technical requirements of the industrial freeze dryer,with a compact and reasonable design,a large redundancy range,and conforms to GMP and FDA standards.The ice condensation capacity is 4~18kg,and the WRL controller and liquid temperature control shelf are adopted,so that the process of pre-freezing and freeze-drying can be precisely controlled on the main machine,and the process results are quite comparable with the production machine.In addition to supporting the eutectic point test system,pressure rise and pressure comparison method to determine the freeze-drying end point and freeze-drying curve recording software,hallan pilot-type freeze dryer can also be equipped with engineering WRL control software to directly Graphical computer control the freeze-drying process.It can be configured with H202 sterilization and high-pressure steam sterilization orintegrated glove box system, which can be used for clean room operation through the wall.The cold trap and freeze-drying chamber are all designed with 316L stainless steel to ensure the cleanliness of the chamber and good ultimate vacuum and vacuum leakage rate to the greatest extent.
Opentrons Flex Magnetic Bead Protein Purification Workstation
Product Info
Document
Product Info
For scaling up and fully automating magnetic bead-based protein purification workflows.
With the Flex Protein Purification Workstation, you can automate your small-scale protein purification and proteomics sample processing at the scale you need to increase efficiency, reduce errors, and save hands-on time. This Opentrons Protein Purification Workstation uses magnetic beads for purification of proteins.
Optional add-ons can be purchased at a 10% discount when ordered with the Flex Magnetic Bead Protein Purification Workstation*
Document
For scaling up and fully automating magnetic bead-based protein purification workflows.
With the Flex Protein Purification Workstation, you can automate your small-scale protein purification and proteomics sample processing at the scale you need to increase efficiency, reduce errors, and save hands-on time. This Opentrons Protein Purification Workstation uses magnetic beads for purification of proteins.
Optional add-ons can be purchased at a 10% discount when ordered with the Flex Magnetic Bead Protein Purification Workstation*
● The double anti-oil return device completely eliminates the damage and
