DBCO-PEG36-TFP ester

Description

Attogene has developed the first of its kind and patent pending technology that uses a novel RNA substrate tagged on the 5′ and 3′ end with a Biotin that is attached to our streptavidin colloidal gold reporter molecules and a test line tag. In the absence of RNases, the gold tagged RNA molecule will flow up the lateral flow strip and bind to the test line using an anti tag antibody (INDICATING that NO RNase is detected). When RNases are present, however, the RNA substrate is cleaved, and the 5′ and 3′ tags are spatially separated in solution cauing the test line to disapear.

  This test can be used to rapidly and efficiently detect ribonucleases in both liquid and on solid surfaces and a perfect tool for monitoring mRNA vaccine manufacturing.  

RNase activity in a convenient and sensitive colormetric assay that delivers results in real time. Great for Quality Testing for RNase contamination of materials and supplies.

Propargyl-PEG5-CH2CO2-NHS is an amine reactive linker with an alkyne moeity which can react with azide-bearing biomolecules in copper catalyzed Click Chemistry reactions. The PEG units enhance the solubility of the linker in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Propargyl-PEG5-CH2CO2-NHS is an amine reactive linker with an alkyne moeity which can react with azide-bearing biomolecules in copper catalyzed Click Chemistry reactions. The PEG units enhance the solubility of the linker in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Description

Formaldehyde is an organic compound with the formula CH2O. It is mainly used in the production of industrial resins but has been found to be used as a preservative, disinfectant and biocide. Because of its toxicity and volatility formaldehyde poses a significant risk to human health. Attogene test uses the property of formaldehyde to react with the Formaldehyde Reaction Powder (FRP) to form a purple-red tetrazine. The formaldehyde concentration is measured by visual comparison of the reaction with the color scale derived from the Color Card.

Where formaldehyde is found

Formaldehyde is found in:

• Resins used in the manufacture of composite wood products (i.e., hardwood plywood, particleboard and medium-density fiberboard)
• Building materials and insulation
• Household products such as glues, permanent press fabrics, paints and coatings, lacquers and finishes, and paper products
• Preservatives used in some medicines, cosmetics and other consumer products such as dishwashing liquids and fabric softeners
• Fertilizers and pesticides

It is a byproduct of combustion and certain other natural processes, and so is also found in:

• Emissions from un-vented, fuel burning appliances, like gas stoves or kerosene space heaters.
• Cigarette smoke.

White Paper from Nix Color Sensor using Attogene’s Formaldehyde Kit: Nix Color Sensor & Attogene Formaldehyde Kit

Attogene test uses the property of formaldehyde to react with the Formaldehyde Reaction Powder (FRP) to form a purple-red tetrazine. The formaldehyde concentration is measured by visual comparison of the reaction with the color scale derived from the Color Card.