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ArcticZymes RNA to DNA Ligase (ArcticZymes R2D Ligase™) is the first ligase on the market that is able to ligate DNA to 5’-phosphorylated ends of RNA in the presence of a DNA template positioning the joinable ends. With its unique substrate specificity, ArcticZymes R2D Ligase allows the development of new technologies in molecular biology research, diagnostics, and manufacturing.
Key Features:
- Novel substrate specificity
- RNA to DNA ligation
- High purity
- Detergent free
- Efficient ligation of DNA to 5’-phosphorylated ends of RNA in the presence of a DNA template positioning the ligatable ends of DNA and RNA
- ATP dependent dsDNA ligase
- Utilizes Mg2+ or Mn2+
Suggested Applications:
- RNA capturing
- In vitro transcription
- NGS library prep
- Transcriptome amplification
- miRNA detection/analysis
- RNA splint ligation
