Description
Specifications
| Clone | IHC001 |
| Source | Mouse Monoclonal |
| Positive Control | Tonsil, Lymph Node |
| Dilution Range | 1:200 |
Programmed Death 1 (PD-1) is a member of the CD28/CTLA-4 family of T-cell regulators, expressed as a co-receptor on the surface of activated T-cells, B-cells, and macrophages. New studies have suggested that the PD-1/PD-L1 signaling pathway may be linked to anti-tumor immunity, as PD-L1 has been shown to induce apoptosis of activated T cells or inhibit activity of cytotoxic T cells. In comparison to CD10 and Bcl-6, PD-1 is expressed by fewer B cells and has therefore been considered a more specific and useful diagnostic marker for angioimmunoblastic T-cell lymphoma. Therapies targeted toward the PD-1 receptor have shown remarkable clinical responses in patients with various types of cancer, including non–small-cell lung cancer, melanoma, and renal-cell cancer.
| Clone | IHC001 |
| Source | Mouse Monoclonal |
| Positive Control | Tonsil, Lymph Node |
| Dilution Range | 1:200 |
This product is specially designed for DNA extraction from forensic samples such as bone, hair, fingernail, seminal strain, dry blood spot, ect. Especially designed for forensic detection. The obtained DNA can be directly used for PCR, STR detection and other down stream applications.
| Contents | D635901D | D635902D | D635903D |
| Purification Times | 48 | 96 | 480 |
| MagPure Particles N | 1.1 ml | 2.2 ml | 11 ml |
| Buffer ATL | 40 ml | 80 ml | 2 x 200 ml |
| Buffer BGL | 40 ml | 80 ml | 2 x 200 ml |
| Buffer BST1 | 60 ml | 120 ml | 550 ml |
| Buffer GW2* | 20 ml | 25 ml | 2 x 50 ml |
| Proteinase K | 48 mg | 110 mg | 2 x 220 mg |
| Protease Dissolve Buffer | 5 ml | 10 ml | 30 ml |
| DTT | 235 mg | 235 mg | 3 x 235 mg |
| Elution Buffer | 10 ml | 10 ml | 30 ml |
32/48 channel machine
| Product | Contents and volume | D6359D-TL-06 |
| Buffer BGL | 80 ml | |
| Buffer ATL | 80 ml | |
| Proteinase K | 110 mg | |
| Protease Dissolve Buffer | 10 ml | |
| DTT Powder | 2 x 235 mg | |
| Elution Buffer | 5 ml | |
| AS-Tip | 12 pcs | |
| 2.0ml V bottom plate | Row 1/7：empty | 6 plates |
| Row 2/8：500μl Buffer BST1 | ||
| Row 3/9：500μl Buffer BST1 | ||
| Row 4/10：20μl MagPure Particles N 500μl Buffer GW2 Row 5/11：500μl Buffer GW2 (ethanol ~350ul) | ||
| Row 6/12：60μl Elution Buffer |
96 channel machine
| Product | Contents and volume | D6359D-F-96 | D6359D-F-48 |
| Buffer BGL | 80 ml | 40 ml | |
| Buffer ATL | 80 ml | 40 ml | |
| Proteinase K | 110 mg | 48 mg | |
| Protease Dissolve Buffer | 10 ml | 5 ml | |
| DTT Powder | 235 mg | 235 mg | |
| Elution Buffer | 5 ml | 5 ml | |
| 96-Tip (AS) | 1 | 1 | |
| Sample Plate 1 | 500μl Buffer BST1 | 1 | 1 |
| Sample Plate 2 | 500μl Buffer BST1 | 1 | 1 |
| Wash Plate 1 | 20μl MagPure Particles N500μl Buffer GW2 | 1 | 1 |
| Wash Plate 2 | 500μl Buffer GW2 | 1 | 1 |
| Elute Plate | 60μl Elution Buffer | 1 | 1 |
Storage and Stability
Proteinase K and DTT Powder should be stored at 2–8°C upon arrival. However, short-term storage (up to 12 weeks) at room temperature (15–25°C) does not affect their performance. The remaining kit components can be stored at room temperature (15–25°C) and are stable for at least 18 months under these condition.
This product is specially designed for DNA extraction from forensic samples such as bone, hair, fingernail, seminal strain, dry blood spot, ect. Especially designed for forensic detection. The obtained DNA can be directly used for PCR, STR detection and other down stream applications.
The Opentrons Flat Bottom Aluminum Block can be placed directly on the OT-2/Opentrons Flex deck or on the Opentrons Temperature Module. This block can hold flat bottom plates and other flat labware at constant temperature. The aluminum block holds temperatures between 4°C and 95°C when used with the Opentrons Temperature Module (GEN2).
The Opentrons Flat Bottom Aluminum Block can be placed directly on the OT-2/Opentrons Flex deck or on the Opentrons Temperature Module. This block can hold flat bottom plates and other flat labware at constant temperature. The aluminum block holds temperatures between 4°C and 95°C when used with the Opentrons Temperature Module (GEN2).
| Clone | IHC697 |
| Source | Mouse Monoclonal |
| Positive Control | Colon Cancer |
| Dilution Range | 1:200 |
Thymidylate Synthase (TS) is a crucial enzyme responsible for the synthesis of 2′-deoxythymidine-5′-monophosphate (dTMP) a precursor for thymidylate which is necessary for DNA replication and repair from 2′-deoxyuridine-5′-monophosphate (dUMP). In terms of cancer, TS is an important target for cancer treatment as the inhibition of TS and therefore nucleotide synthesis necessary for cell growth has shown to be a vital part for successful treatment against colorectal, pancreatic and breast cancers.
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