Postmeiotic Segregation Increased 2 (PMS2) is a DNA repair protein involved in mismatch repair. Mutations and deficiencies in the PMS2 gene have been linked to microsatellite instability, and malignancies such as hereditary nonpolyposis colorectal cancer and endometrial cancer. Expression levels of the PMS2 protein may be useful as a screening tool for Lynch syndrome after a colorectal cancer diagnosis. Anti-PMS2 is recommended to be used as part of a panel along with antibodies against MLH1, MSH2, and MSH6.
Protein A Colloidal Gold for Lateral Flow (1mL)
Product image shows functional testing of Protein A 40nm colloidal gold on a lateral flow test. Protein A 40nm colloidal gold was incubated in lateral flow running buffer alone or in the presence of a limiting amount of monoclonal antibody that targets the chemical-BSA conjugate. The gold was then applied to the sample port of a cassette containing a lateral flow strip sprayed with a chemical conjugate (Chemical-BSA) on the test line and a goat anti mouse antibody as the control line. The data demonstrates the specificity and robustness of the Protein A 40nm colloidal gold.
Our products are produced in a state-of-the-art manufacturing facility that enable rapid turnaround times while ensuring batch to batch consistency and reliability.
Functionally tested Protein A conjugated gold
Perfect for Lateral Flow Development and use in final product
40nm gold particles conjugated to Protein A are offered in 10 OD 1mL size. If a different OD or amount is required please
Tri(propargyl-NHCO-ethyloxyethyl)amine is a crosslinker that can react with azide compounds or biomolecules via copper catalyzed Click Chemistry to form a stable triazole linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Tri(propargyl-NHCO-ethyloxyethyl)amine is a crosslinker that can react with azide compounds or biomolecules via copper catalyzed Click Chemistry to form a stable triazole linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Our SNPsig® kits use our own proprietary genotyping method to enable the identification of SARS-CoV-2 variants of concern. These products can be used on any real-time PCR machine using familiar protocols, whilst resulting in exceptional genotyping data.
Positive control templates for wild-type and variants are supplied in every kit to make data interpretation simple.
SNPsig® EscapePLEX™ SARS-CoV-2 also incorporates the two gene (ORF1ab and M Gene) assay to provide a confirmatory detection of SARS-CoV-2.
DETECTION PROFILE: The E484K, K417N, K417T and P681R mutations which are found in Beta, Gamma, Delta and Delta Plus Variants of Concern
Rapid detection of specific detection profiles
High priming efficiency
Sensitive to < 100 copies of target
Positive copy number standard curve for quantification
Accurate controls to confirm findings
96 reactions
