GeneAb™ SOX10

Facebook
X
Pinterest
Email

SRY (Sex Determining Region Y)-Box 10 (SOX-10), also known as transcription factor SOX-10, is a nuclear transcription factor that acts in regulation of embryonic development and in the specification and differentiation of cells of melanocytic lineage. SOX-10 is diffusely expressed in neurofibromas and schwannomas, and mutations in the SOX-10 gene are linked to Waardenburg-Shah and Waardenburg-Hirschsprung disease. Anti-SOX-10 has been shown to be sensitive for conventional, spindled, and desmoplastic melanoma, and has been used to detect metastatic melanoma and nodal capsular nevus in sentinel lymph nodes.

Detail

Description

Specifications

CloneIHC010
SourceMouse Monoclonal
Positive ControlMelanoma, Skin Melanocytes
Dilution Range1:200

Other Products

[RQ2110] ExcelRT™ One-Step RT-qPCR Kit (TaqMan, ROX), 200 RXN

ProteoSpin™ Inclusion Body Protein Isolation Kits

6x10ml PRP Centrifuge Rotor