PEG3-(Amino-Tri-(Propargyl-PEG2-ethoxymethyl)-methane)-(Amino-Tri-(endo-BCN-PEG2-ethoxymethyl)-methane)

N-(Amine-PEG8)-N-bis(PEG8-Propargyl) is a trifunctional linker containing an amino group and two terminal alkynes. These alkynes are frequently used in copper (I) click reactions with azides to form stable triazole linkages, while the primary amine is reactive towards carboxylic acids and other carbonyl compounds such as NHS esters, aldehydes or ketones.

N-(Amine-PEG8)-N-bis(PEG8-Propargyl) is a trifunctional linker containing an amino group and two terminal alkynes. These alkynes are frequently used in copper (I) click reactions with azides to form stable triazole linkages, while the primary amine is reactive towards carboxylic acids and other carbonyl compounds such as NHS esters, aldehydes or ketones.

PEG3-bis(Amino-Tri-(Propargyl-PEG8-ethoxymethyl)-methane) is large molecule with two sets of three terminal alkynes joined together by a short PEG linker. The alkynes are most frequently used in copper click chemistry with azides to form stable triazoles with the target compound. The PEG linkers as well as numerous amide bonds provide high aqueous solubility to this compound, which may alter DMPK of this compound.

PEG3-bis(Amino-Tri-(Propargyl-PEG8-ethoxymethyl)-methane) is large molecule with two sets of three terminal alkynes joined together by a short PEG linker. The alkynes are most frequently used in copper click chemistry with azides to form stable triazoles with the target compound. The PEG linkers as well as numerous amide bonds provide high aqueous solubility to this compound, which may alter DMPK of this compound.

Overview

• Detection kits for the VZV
• CE-IVD marked version available for in vitro diagnostic use
• Available in TaqMan format for analysis

Varicella zoster virus (VZV) is one of eight herpes viruses known to infect humans and other vertebrates. VZV commonly causes chicken-pox in children and both shingles and postherpetic neuralgia in adults. Primary VZV infection results in chickenpox, which may rarely result in complications including encephalitis or pneumonia. VZV, like other herpes viruses, remains dormant in the nervous system of the infected person, and in 10-20% of cases the VZV reactivates later in life producing a disease known as herpes zoster or shingles. Serious complications of shingles include postherpetic neuralgia, zoster multiplex, myelitis, herpes ophthalmicus, or zoster sine herpete.

VZV TaqMan PCR Kit, 100 reactions

• Ready to use format, including Master Mix for the target and PCR control to monitor for PCR inhibition and validate the quality
• Specific Primer and Probe mix for the pathogen/virus/viroid of interest
• Primer and Probe mix
• Positive and negative control to confirm the integrity of the kit reagents

VZV TaqMan PCR Probe/Primer Set and Controls, 100 reactions

• Specific Primer/Probe mix and Positive Control for the pathogen/virus/viroid of interest
• Nuclease-free water
• Can be used together with Norgen’s PCR Master Mix (#28007) or customer supplied master mix

Details

Supporting Data

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Storage Conditions and Product Stability
All kit components can be stored for 2 years after the date of production without showing any reduction in performance.

All kit components should be stored at -20°C upon arrival. Repeated thawing and freezing (> 2 x) of the Master Mix and Positive Control should be avoided, as this may affect the performance of the assay. If the reagents are to be used only intermittently, they should be frozen in aliquots.

Component	Cat. TM36750 (100 preps)	Cat. TM36710 (100 preps)
MDx TaqMan 2X PCR Master Mix	2 x 700 μL	–
VZV Primer & Probe Mix	280 μL	280 μL
VZV Positive Control	150 μL	150 μL
Nuclease-Free Water (Negative Control)	1.25 mL	1.25 mL
Product Insert	1	1